MALAYSIA-PRESS-Petronas eyes oil well exploration in Sri Lanka-Malaysian Reserve

Petroliam Nasional Bhd (Petronas) is considering oil well explorations off the shores of Sri Lanka, possibly near the Palk Straits and the Mannar Basin bordering India and the island state.

It is learnt that the government of Sri Lanka has invited Petronas, through the Malaysian government, to study and review the possibly of working together in exploiting oil and gas (O&G) resources in the straits and the Mannar basin.

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Axiata in Myanmar telecoms race-The Star

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NOTE: Reuters has not verified this story and does not vouch for its accuracy. (Reuters) Keywords: MALAYSIA PRESS/

(Kuala Lumpur newsroom, +603 2333-8046, fax +603 2161-3340, areuters@gmail.com)

COPYRIGHT

Copyright Thomson Reuters 2012. All rights reserved.

The copying, republication or redistribution of Reuters News Content, including by framing or similar means, is expressly prohibited without the prior written consent of Thomson Reuters.

Source: http://www.xe.com/news/2012/10/08/2975089.htm?utm_source=RSS&utm_medium=TL&utm_content=NOGEO&utm_campaign=News_RSS_Art5

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Feeling lonely? Vest hugs you whenever you get a 'Like'

28 min.

While many smartphones can notify you when you get a Facebook like with a cheerful ringtone or pop-up, this vest takes it a step further and actually gives you a friendly squeeze.

The "Like-A-Hug"?vest is a project by Melissa Kit Chow at the?MIT Media Lab. She wanted?to bridge the distance that separates people using social media ? after all, as much as you like or comment on someone's photo or post, it's not the same as being there.

Collaborating with MIT colleagues?Andy Payne and Phil Seaton, she made?this vest, which stays connected to the Internet (presumably through your smartphone) and inflates whenever someone likes something of yours on Facebook.

It's just an art project at this point and very unlikely to be made into a real project, but it's easy to imagine the concept being applied in a more subtle way: a jacket that taps you on the shoulder when you get a text message, for instance.

A little more info on the Like-A-Hug vest and Chow's other work?can be found at her site.

Devin Coldewey is a contributing writer for NBC?News Digital. His personal website is coldewey.cc.

Source: http://www.nbcnews.com/technology/gadgetbox/feeling-lonely-vest-hugs-you-whenever-you-get-6282275

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Datalink lowers 3Q outlook, stock takes big hit

EDEN PRAIRIE, Minn. (AP) ? Data-center services company Datalink Corp. lowered its outlook for third-quarter revenue and net income on Thursday saying its customers remain wary of making large capital outlays in the uncertain economy.

Its stock shed 16 percent in after-market trading on the news.

Datalink said it saw some customers push back expected contracts 90 days or more due to their uncertainty over the economy's direction.

"This customer behavior has caused us to miss our previous guidance," CEO Paul Lidsky said.

The company now expects to post third-quarter earnings of 14 to 15 cents per share on an adjusted basis. That's compared with its prior forecast of 20 to 25 cents. Analysts polled by FactSet were expecting the company to earn an adjusted 23 cents per share.

It forecast third-quarter revenue in the range of $105 million to $106 million, versus its prior forecast of $117 million to $122 million. Analysts were expecting $120.4 million.

Datalink's stock fell $1.38 to $7.20 in extended trading following the release of its updated guidance. It will report its full third-quarter results on Oct. 25.

The company, based in Eden Prairie, Minn., also said Thursday that it completed its $13.2 million acquisition of Strategic Technologies Inc. The deal will boost Datalink's market share and increase its presence on the East Coast.

Datalink expects the deal will add to its earnings within one quarter. It will record a charge of about $300,000, or 1 cent per share, in its fourth quarter as a result of the deal.

The acquisition follows its purchase of another information technology services company, Midwave Corp., in October 2011.

Source: http://news.yahoo.com/datalink-lowers-3q-outlook-stock-takes-big-hit-221721271--finance.html

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France set to ease 2013 tax hikes on small business

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Source: http://news.yahoo.com/france-could-ease-2013-tax-hikes-small-firms-064729855--finance.html

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Monster Katana Ears-On: This Sounds Too Good to Be Bluetooth [Audio]

I just got a chance to listen to Monster's forthcoming Katana, a six-speaker, 400-watt (!), Bluetooth system, and it's incredible. A Bluetooth audio system has never sounded better. Monster's new innovations in wireless technology might be the next big thing. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/QBD0kizs2Bw/monster-katana-ears+on-this-sounds-too-good-to-be-bluetooth

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Taylor Hanson Welcomes Daughter Wilhelmina Jane

"Natalie and I are thrilled to announce the arrival of our newest family member, Wilhelmina Jane Hanson," Taylor tells PEOPLE exclusively. "She arrived on Tuesday, Oct. 2, and was welcomed by more love than could fit in the room."

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/pD2ygXOvBPY/

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Trojan horse drug therapy provides new approach to treating breast cancer

Wednesday, October 3, 2012

When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease.

An administrative assistant in the Department of Chemistry at Wake Forest University, Tuttle was more accustomed to talking to faculty and staff about meetings and course loads ? not doctors' appointments and treatment plans.

But after her 2009 diagnosis, Tuttle's use of tamoxifen, a drug commonly used to treat breast cancer, inspired medicinal chemist Ulrich Bierbach to develop a targeted therapy that delivers a sneak attack to the disease, similar to a Trojan horse.

Trojan horses and targeted warheads

Current platinum-based drugs, such as the blockbuster drug cisplatin, do not work on the most common and most difficult-to-cure types of cancer, including lung and breast.

Building upon more than a decade's work in platinum-based drug research, Bierbach's team now designs synthetic hybrid molecules that more effectively tackle otherwise chemo-resistant cancers, including breast cancer. Results of this work, funded by the National Cancer Institute at the National Institutes of Health, appear in the September 13 issue of the Journal of Medicinal Chemistry.

Results also have led to tumor-seeking magic bullets that attach platinum to endoxifen, a close relative of tamoxifen, and quietly hitch a ride to the diseased cells, as if hidden in a Trojan horse.

"Platinum-based drugs cause severe damage to the DNA in cancer cells. Unfortunately, most cancers are smart enough to cut out the DNA damage and repair it, and that's the starting point for our structural design. We developed a compound that does a good job therapeutically by overwhelming the 'damage repair police' of the cell," said Bierbach, a chemistry professor who recently completed a four-year term with the California Breast Cancer Research Program.

Bierbach said that instead of killing certain cancer cells, cisplatin causes kinks in the DNA strand, which prompt cell enzymes to repair the damage. Wake Forest's new platinum-based molecule has a much higher affinity for DNA than cisplatin and twists it in a way that is not easily identified by the cancerous cell.

Initial preclinical studies have proven Bierbach's army of molecules to be 500 times more powerful than cisplatin in treating non-small cell lung cancer, 80-100 times for pancreatic cancer and up to 10 times for breast cancer.

"Within the next two years, we hope to turn our platinum-based drugs into safer, targeted warheads by attaching them to vehicles that will take them to a specific type of cancer and act as a guided missile," he said.

Hope on the horizon

Offering a safer way of delivery will be an important step in convincing industrial partners and the Food and Drug Administration (FDA) to move forward with clinical testing, which Bierbach estimates could be another three to four years away. Still, he and Tuttle remain encouraged given the progress to date.

For nearly three years, they met several times a week to explore Tuttle's treatment options, discuss possible side effects, and defuse her fears.

"My grandmother had breast cancer. We were even the same age when we were diagnosed," said Tuttle. "Now every time I have a strange pain or a headache, I can't help but wonder if I have another tumor."

But unlike her grandmother, whose late stage breast cancer metastasized, Tuttle's cancer was only stage 1 when a routine mammogram detected it. Today she is in remission following a lumpectomy and radiation therapy, and her quality of life has improved.

Though her prognosis looks promising, she and Bierbach still get together frequently in the halls of the chemistry department to share stories ? hers of how she now lives every day to its fullest, and his of the lab's progress with its challenging research projects.

"Our professional relationship has definitely grown," said Tuttle. "I hope his research group stays as focused as it is now. Every advancement helps."

"Wake Forest's motto is Pro Humanitate, which means 'for humanity,' and it motivates our research group daily," Bierbach added. "Everyone knows someone who has been affected by cancer, and there's a pressing need for more effective and less toxic chemotherapies. The solution starts with some combination of academic curiosity and personal experience, and takes place in a lab that has synthetic chemistry expertise and a good deal of imagination to think about new ways to tackle cancer mechanistically at the molecular level. It's a fulfilling job, but it's even more rewarding to help someone you know."

###

Wake Forest University: http://www.wfu.edu

Thanks to Wake Forest University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/124066/Trojan_horse_drug_therapy_provides_new_approach_to_treating_breast_cancer_

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Living Life In Costa Rica blog: TATTOO CONVENTION Costa Rica


The tattoo convention is back at Club Moon Saturday with live music, tattoo tents and presentations from famous artists. Courtesy of Paradise International Tattoo Convention

Sorry for the delay in posting this but I JUST saw it and I'm posting it in case someone interested in Tattoo's in Costa Rica seeks some leads on it.
WHEN:? Saturday and Sunday - September 29 and 30, 2012

WHERE:? CLUB MOON Nightlife and Business - Frente a las Bodegas de Florida Ice a
I'm sharing this info AFTER the fact in case anyone is seeking info on Tattoos in Costa Rica - or for next years Tattoo Convention.

ESPANOL:
Fue en el a?o 2010 que se inici? este proyecto como ?Expo Tattoo Costa Rica? con la empresa Freak Productions y su organizador Andy Morales, para unificar el arte corporal entre artistas nacionales.

Poco a poco fue creciendo y madurando la idea y ahora en el 2012 se presenta la tercera fecha del mismo evento como ?PARADISE? Tattoo Convention Costa Rica 2012, junto a Nueva Calavera JLO S.A. y Johnn L?pez, con un esquema e ideas diferentes para seguir mejorando la industria y unir a m?s artistas de gran trayectoria, adem?s de dar oportunidades para profesionales donde reciban seminarios educativos, informaci?n de proveedores y al p?blico en general un excelente entretenimiento e informaci?n sobre esta tendencia cultural.

Para este a?o 2012 contaremos con la participaci?n del gran artista y modificador corporal Lukas Zpira desde Francia.

?PARADISE? Tattoo Convention Costa Rica2012 se realizar? los d?as viernes 28 de septiembre con un seminario impartido por dicho invitado especial con un cupo limitado, en donde se impartir?n temas importantes sobre body piercing y modificaciones corporales.

El gran show para artistas en general y p?blico presente se llevar?n a cabo los d?as 29 y 30 de septiembre en donde abr?n shows continuos de m?sica en vivo, pasarela de marcas nacionales e internacionales, freak show, demostraci?n de skate, premiaci?n a mejor tatuaje de la convenci?n, miss pin up "CHICA PARADISE" 2012, body paint y mucho mas.

El lugar de la convenci?n ser? en el Club Moon Nightlife & Business Frente a las Bodegas de Florida Ice & Farm San Joaqu?n de Heredia el 29 y 30 de septiembre

Las entradas estar?n a la venta en los estudios participantes y lugares patrocinadores y tendr?n un precio de 5mil colones por d?a o una promoci?n de 16mil por 4 entradas.

Por ustedes y por la industria es que trabajamos fuerte en este proyecto, sigamos manteniendo nuestro apoyo que ya lo ha sido por tres fechas consecutivas y seamos de esto una sola unidad

EL SEMINARIO EDUCATIVO SERA IMPARTIDO POR EL GRAN MODIFICADOR LUKAS ZPIRA DESDE FRANCIA SOBRE MODIFICACIONES CORPORALES EL DIA VIERNES 28 DE SEPTIEMBRE A LAS 10AM EN LAS INSTALACIONES DE NEW SKULL EN SAN PEDRO E INCLUYE:
* CERTIFICADO DE PARTICIPACIO* GAFETES
* PROCEDIMIENTOS EN VIVO CON EL ARTISTA PARA ALGUNOS DE LOS PARTICIPANTES
* TRADUCTOR
* MATERIAL
* REFRIGERIO

ENTRE OTROS METODOS Y CONSULTAS A TRATAR

COSTO POR PERSONA: $150 CUPO LIMITADO DE 30 Y EXCLUSIVO PARA ARTISTAS DE ESTUDIOS

INFORMACION DE STANDS
* 3X3
* MESA
* ELECTRICIDAD
* 4 PARES DE GUANTES
* 2 CAMPOS ESTERILES
* AGUA
* 2 SILLAS
* BOLSA DE DESECHO
* BOTE DE DESECHO BIOPELIGROSO
* GAFETES

Para m?s informaci?n de stands y del evento en general pueden contactar a:

ENGLISH
It was in 2010 that started this project as "Costa Rica Tattoo Expo" with the company Freak Productions and organizer Andy Morales, to unify body art among artists.Little by little the idea grow and mature in 2012 and now presents the third round of the same event as "PARADISE" Costa Rica Tattoo Convention 2012, alongside New Skull JLO SA Johnn and Lopez, with a scheme and different ideas to further improve the industry and unite more artists of great experience, in addition to providing opportunities for professionals where they receive educational seminars, information providers and the general public an excellent entertainment and information on this cultural trend.For this year 2012 will have the participation of the great artist and body modifier Lukas Zpira from France."PARADISE" Costa Rica2012 Tattoo Convention will be held on Friday, September 28 with a seminar given by the special guest with limited space where important topics are taught about body piercing and body modification.The great show for artists and general audience will be held on 29 and 30 September where Abram shows continuous live music, gateway national and international brands, freak show, skate demo, awards for the best tattoo convention, miss pin up "girl PARADISE" 2012, body paint and much more.The venue of the convention will be at Club Moon Nightlife & Business Facing Bodegas Florida Ice & Farm San Joaquin de Heredia on 29 and 30 SeptemberTickets will be on sale in studies sponsors and participants and places will cost colones per day 5mil or 16mil promotion for 4 tickets.For you and for the industry is that we work hard on this project, we maintain our support and has been for three consecutive dates and let this one unit
EDUCATIONAL SEMINAR will be taught by LUKAS MODIFIER GREAT FROM FRANCE ON Zpira body modifications on Friday, September 28 at 10am at SKULL NEW FACILITY IN SAN PEDRO AND INCLUDES:* CERTIFICATE Participaci? * BADGES* PROCEDURES LIVE WITH ARTIST FOR SOME OF THE PARTICIPANTS* TRANSLATOR* MATERIAL* SNACKOther methods and consultations TREATCOST PER PERSON: $ 150 SPACE IS LIMITED TO 30 EXCLUSIVE FOR ARTISTS AND STUDYINFORMATION STANDS* 3X3* TABLE* ELECTRICITY* 4 pairs of gloves* 2 sterile fields* WATER* 2 CHAIRS* Waste bag* JAR biohazardous waste* BADGESFor more information booth and the event in general can contact:

Oficinas: (506) 2-524-2973? ?? ParadiseTattooConvention@hotmail.com

Johann L?pez:? (506) 8-834-8255? ?? johannlop@hotmail.com
Andy Morales:? (506) 8-655-8963? ?? andriska25@hotmail.com

Dale Like a nuestro facebook y participa en entradas y promociones el d?a del evento

facebook.com/pages/Paradise-Tattoo-Convention/442597739108322
facebook.com/pages/Johann-Lopez-Official/212975718735432

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Source: http://livinglifeincostarica.blogspot.com/2012/10/tattoo-convention-costa-rica.html

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